Brian L. Foster, PhD

Associate Professor

Central Michigan University, 2000, Microbiology

University of Washington, 2011, Oral Biology

Research Interests

I study the molecular biology of tooth root development and mineralization, with interests including genes, mechanisms, diseases, and novel regeneration strategies.

Research Summary

My overarching objective as a researcher in the dental-oral-craniofacial field is to understand the molecular mechanisms driving tooth root formation and bring that insight to novel approaches for regenerating tissues and restoring function. To date, specific areas of inquiry have included phosphate/pyrophosphate metabolism and dentoalveolar development and regeneration, developmental regulators of cementum, functions of extracellular matrix proteins in dental development and mineralization, and manifestations of skeletal and endocrine diseases in the craniofacial and dental tissues. More broadly, I am also interested in how knowledge gained from the study of dental-oral-craniofacial connective tissues may also be applied to skeletal development, disease, wound healing, and regeneration.

Research Support

09/01/19 - 08/31/24
Functions of extracellular matrix proteins in dental and skeletal mineralization

06/15/19 - 05/31/21
Role of tissue-nonspecific alkaline phosphatase in dentoalveolar development and disease

06/18/19 - 06/18/20
Clinical Scholars Grant OSU College of Dentistry
Genetic and dental analysis of a novel form of dentinogenesis imperfecta

04/01/19 - 03/31/21
R03 NIDCR                                                                     
Function of cementocytes in cellular cementum formation and resorption

05/01/18 - 06/30/20
Ultragenyx Pharmaceuticals
Effects of KRN23 (UX023) on Dental Mineralization in X-linked Hypophosphatemia

Courses Taught

Course Director:

DENT 6500 Histology, Development, and Cell Biology of Oral Tissues
DENT 7921 Oral Biology Journal Club
DENT 8008 Advanced Histology and Embryology
DENT 8840 Oral Biology Current Issues

Brian Foster
Office Address

4163 Postle Hall
305 W. 12th Avenue
Columbus, OH 43210
United States

Lab Address

4010 Postle Hall
305 W. 12th Avenue
43210 OH

Academic Division